2. Agonist interaction
If drugs and CBD have the same effects, they can be mutually reinforcing. This "double" action can then be too much for someone and it is therefore not appropriate for them to combine both. An example is a blood pressure lowering drug. If we also use CBD, which, among other things, can effectively reduce the pressure in the arteries, we may begin to suffer from dizziness, fainting and other symptoms of too low a pressure.
While CBD alone does not overdose you, in combination with prescription pills, it can lead to an effect that is too strong.
3. Antagonistic interaction
An antagonistic interaction is the exact opposite of an agonistic interaction. It is that while the CBD strengthens something, the drug weakens it. Or vice versa. In short, they are contradictory and disruptive to each other.
In this case, there is usually no direct side effect, but simply a situation where no effect occurs at all. The cannabinoid and the drug are neutralized. A classic example in this case is the combination of soothing CBD and stimulants.